for oral use Initial U.S. Approval: 2020
Tazverik (tazemetostat) is a medication used for the treatment of epithelioid sarcoma that is locally advanced (when the cancer is growing outside of the organ, but has not yet spread) or metastasized (when cancer cells have spread to other parts of the body) and that cannot be completely removed by surgery, and for relapsed or refractory follicular lymphoma.
Facts about tazemetostat tablets
Disease Indications-Soft Tissue Sarcoma
Medicine Approved By-Food and Drug Administration (FDA), Pharmaceuticals and Medical Devices Agency (PMDA)
Summary of FDA-approved use on approval date: Click Here
(see Drugs@FDA for complete indication)
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Approved accessible "tazemetostat tablets"
Tazemetostat blocks the action of a protein called EZH2. Some patients with malignant mesothelioma produce large amounts of the EZH2 protein, which encourages abnormal growth and development of mesothelial cells. By blocking EZH2, tazememostat is expected to lead to the death of the mesothelial cells and thus reduce the growth of the cancer.
The US FDA approved TAZEMETOSTAT for treating patients aged above 16 years with metastatic or locally advanced epithelioid sarcoma who cant undergo complete resection. It should be taken as 800 mg taken orally twice daily with or without food. It can increase the risk of developing secondary cancers like lymphoma, leukemia, etc. It can cause fetal harm. So, patients should use effective non-hormonal contraception. Common side effects reported with TAZEMETOSTAT are pain, fatigue, nausea, decreased appetite, vomiting etc.
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TAZVERIK (tazemetostat) tablets, for oral use Initial U.S. Approval: 2020
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