Indian Pharma Network (IPN)
Medicines For Neuro Oncology Treatment
IPN, New Delhi can facilitate Neuro Oncology patient to “import of Medicines For Neuro Oncology Treatment” for personal use under “patient name basis” treatment in India. For this applicant is required to make an request application with required document. IPN, New Delhi will do the necessary process to obtain permission from Drugs Controller General (India) to import.
Indian Pharma Network
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Neuro Oncology Treatment
Neuro-oncology is a branch of medicine that focuses on the diagnosis and treatment of tumors of the brain and nervous system. Neuro-oncologists work closely with other specialists such as neurosurgeons, radiation oncologists, and neuropathologists to provide comprehensive care for patients with brain and nervous system tumors.
The field of neuro-oncology encompasses a wide range of tumor types, including:
- Gliomas: These are tumors that develop in the glial cells that support the nerve cells in the brain and spinal cord. They are the most common type of brain tumor.
- Meningiomas: These are tumors that develop in the lining of the brain and spinal cord.
- Pituitary tumors: These are tumors that develop in the pituitary gland, a small gland located at the base of the brain that regulates many bodily functions.
- Schwannomas: These are tumors that develop in the Schwann cells that surround nerve cells.
- Medulloblastomas: These are tumors that develop in the cerebellum, the part of the brain that controls movement and balance.
The treatment of neuro-oncology involves a multidisciplinary approach that may include surgery, radiation therapy, chemotherapy, and targeted therapy. The choice of treatment depends on the type, location, and size of the tumor, as well as the patient’s age and overall health. The goal of treatment is to remove or control the tumor while minimizing damage to surrounding healthy tissue and preserving neurological function.
Get Access FDA Approved Medicines For Neuro Oncology Treatment
There are several chemotherapy drugs that can be used in the treatment of neuro-oncology, which includes:
- Temozolomide: This is a chemotherapy drug commonly used to treat gliomas, which are tumors that start in the brain or spinal cord. It is often given in combination with radiation therapy.
- Carmustine (BCNU): This is a chemotherapy drug that is used to treat brain tumors such as gliomas and lymphomas. It is typically given as an implant that is placed directly into the tumor during surgery.
- Procarbazine: This is a chemotherapy drug that is used to treat brain tumors such as gliomas, lymphomas, and meningiomas.
- Lomustine (CCNU): This is a chemotherapy drug that is used to treat gliomas and other brain tumors.
- Methotrexate: This is a chemotherapy drug that is used to treat primary central nervous system lymphomas (PCNSL) and other brain tumors.
- Cisplatin: This is a chemotherapy drug that is used to treat brain tumors such as medulloblastomas.
Targeted therapy drugs are a class of medications that are used to treat cancer by targeting specific molecules that are involved in the growth and spread of cancer cells. In neuro-oncology, targeted therapy drugs are used to treat brain tumors, including gliomas, meningiomas, and neuroblastomas. Some common targeted therapy drugs used to treat brain tumors include:
- EGFR inhibitors: These drugs target a protein called epidermal growth factor receptor (EGFR), which is found in some types of brain tumors. Examples of EGFR inhibitors used to treat brain tumors include erlotinib and gefitinib. They work by blocking the activity of EGFR, which helps slow or stop the growth of cancer cells.
- VEGF inhibitors: These drugs target a protein called vascular endothelial growth factor (VEGF), which helps tumors grow new blood vessels to supply them with nutrients and oxygen. Examples of VEGF inhibitors used to treat brain tumors include bevacizumab and aflibercept. They work by blocking the activity of VEGF, which helps reduce the blood supply to tumors and slows their growth.
- BRAF inhibitors: These drugs target a specific genetic mutation (BRAF) that is found in some types of brain tumors, including melanoma brain metastases. Examples of BRAF inhibitors used to treat brain tumors include dabrafenib and vemurafenib. They work by blocking the activity of mutated BRAF, which helps slow or stop the growth of cancer cells.
- ALK inhibitors: These drugs target a genetic mutation called anaplastic lymphoma kinase (ALK), which is found in some types of brain tumors, including anaplastic oligodendroglioma. Examples of ALK inhibitors used to treat brain tumors include crizotinib and ceritinib. They work by blocking the activity of mutated ALK, which helps slow or stop the growth of cancer cells.
Immunotherapy is an emerging treatment option for neuro-oncology that aims to boost the immune system’s ability to recognize and destroy cancer cells. Currently, there are several types of immunotherapy medicines that are being used in clinical trials to treat brain tumors. Some of the immunotherapy medicines that have shown promise in early studies include:
- Checkpoint inhibitors: These drugs block certain proteins on cancer cells, preventing them from evading the immune system. Checkpoint inhibitors that are being tested in clinical trials for neuro-oncology include pembrolizumab and nivolumab.
- T-cell therapies: These treatments involve removing T-cells (a type of immune cell) from the patient’s blood and genetically modifying them to recognize and attack cancer cells. T-cell therapies that are being tested in clinical trials for neuro-oncology include CAR T-cell therapy.
- Vaccines: These treatments involve using a patient’s own tumor cells or specific proteins found on tumor cells to stimulate the immune system to recognize and attack cancer cells. Vaccines that are being tested in clinical trials for neuro-oncology include dendritic cell vaccines and peptide vaccines.
- Immune-modulating drugs: These treatments work by regulating the immune system, either by activating it or suppressing it. Immune-modulating drugs that are being tested in clinical trials for neuro-oncology include interferon alpha and interleukin-2.
These drugs are used to reduce inflammation and swelling in the brain caused by the tumor
The specific medications used for neuro-oncology treatment will depend on the individual patient’s case, including the type and stage of the tumor, as well as the patient’s age and overall health. The healthcare team will work to determine the best treatment plan for each individual patient based on their case and the current state of research in the field.
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