for subcutaneous use Initial U.S. Approval: 2010
denosumab injection is a RANK ligand (RANKL) inhibitor indicated for: • Prevention of skeletal-related events in patients with bone metastases from solid tumors • Treatment of adults and skeletally mature adolescents with giant cell tumor of bone that is unresectable or where surgical resection is likely to result in severe morbidity.
Facts about denosumab injection
Approval Date: 1970
Proprietary Name: On Request
Active Ingredient(s): denosumab injection
Dosage Forms And Strengths: 120 mg/1.7 mL (70 mg/mL) single-use vial
Manufacturer: Amgen Inc.
Medicine Approved By: – European Medical Agency (EMA), Food and Drug Administration (FDA), Health Canada, Therapeutic Goods Administration (TGA), Medsafe (NZ)
Summary of FDA approved use on approval date: Click Here
(see Drugs@FDA for complete indication)
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Query For denosumab injection
Approved accessible "denosumab injection"
Denosumab is approved to treat:
- Giant cell tumor of the bone that cannot be removed by surgery. It is used in adults and in adolescents whose bones have finished growing.
- Hypercalcemia of malignancy that got worse after treatment with bisphosphonates.
- These uses are approved for the Xgeva brand of denosumab.
Denosumab is approved to prevent:
Broken bones and other bone problems caused by multiple myeloma or by solid tumors that have metastasized (spread) to bone. This use is approved for the Xgeva brand of denosumab.
Denosumab is also approved to increase bone mass in adults who have a high risk of breaking bones. It is used in the following types of cancer:
- Breast cancer in women receiving aromatase inhibitor therapy.
- Prostate cancer in men receiving androgen deprivation therapy.
- These uses are approved for the Prolia brand of denosumab.
How can 1 go about obtaining denosumab injection?
If denosumab injection are not yet approved or available in your area, you may request its price in India under a specific brand name through IPN. For assistance and guidance, you can contact us by providing complete details. Our pharmaceutical expert will help you find a suitable and practical solution to your query. To receive comprehensive support, please call us at +91 9891 296 838 (Mr. Tarun) / +91 9811 747 774 (Mr. Neeraj).
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