LONSURF is a combination of trifluridine, a nucleoside metabolic inhibitor, and tipiracil, a thymidine phosphorylase inhibitor, indicated for the treatment of patients with metastatic colorectal cancer who have been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy.
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The order for LONSURF (trifluridine and tipiracil) tablets will be confirmed only after the receipt of valid prescription of doctor and import permit if applicable.
Trifluridine/tipiracil (trade name Lonsurf) is a combination drug that is used as a third- or fourth-line treatment of metastatic colorectal cancer, after chemotherapy and targeted therapeutics have failed. It is a combination of two active pharmaceutical ingredients: trifluridine, a nucleoside analog, and tipiracil, a thymidine phosphorylase inhibitor. Tipiracil prevents rapid metabolism of trifluridine, increasing the bioavailability of trifluridine.
LONSURF (trifluridine and tipiracil) tablets, for oral use Initial U.S. Approval: 2015
Generic Name: Olaparib
• 15 mg trifluridine/6.14 mg tipiracil
• 20 mg trifluridine/8.19 mg tipiracil
IPN helps patients, doctors and hospitals as a facilitator to import prescription medicine brand LONSURF (trifluridine and tipiracil) tablets on prescription and Import License in Patient's Name only.
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