SUTENT is a kinase inhibitor indicated for the treatment of • Gastrointestinal stromal tumor (GIST) after disease progression on or intolerance to imatinib mesylate. • Advanced renal cell carcinoma (RCC). • Progressive, well-differentiated pancreatic neuroendocrine tumors (pNET) in patients with unresectable locally advanced or metastatic disease.
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Sunitinib (marketed as Sutent by Pfizer, and previously known as SU11248) is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) on January 26, 2006. Sunitinib was the first cancer drug simultaneously approved for two different indications
SUTENT® (sunitinib malate) capsules, oral Initial U.S. Approval: 2006
Generic Name: sunitinib malate
Capsules: 12.5 mg, 25 mg, 50 mg.
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