FOLOTYN is a folate analogue metabolic inhibitor indicated for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). This indication is based on overall response rate. Clinical benefit such as improvement in progression free survival or overall survival has not been demonstrated.
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Pralatrexate (brand name Folotyn) is an anti-cancer therapy. It is the first drug approved as a treatment for patients with relapsed or refractory peripheral T-cell lymphoma, or PTCL — a biologically diverse group of aggressive blood cancers that have a poor prognosis..
FOLOTYN (pralatrexate injection) Solution for intravenous injection. Initial U.S. Approval: 2009
Generic Name: pralatrexate
Sterile, single-use vials containing pralatrexate at a concentration of 20 mg/mL in the following presentations:
- 20 mg of pralatrexate in 1 mL solution in a vial (20 mg / 1 mL)
- 40 mg of pralatrexate in 2 mL solution in a vial (40 mg / 2 mL)
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