LARTRUVO™ is a platelet-derived growth factor receptor alpha (PDGFR-α) blocking antibody indicated, in combination with doxorubicin, for the treatment of adult patients with soft tissue sarcoma (STS) with a histologic subtype for which an anthracycline-containing regimen is appropriate and which is not amenable to curative treatment with radiotherapy or surgery.
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Olaratumab (trade name Lartruvo) is a monoclonal antibody developed by Eli Lilly and Company for the treatment of solid tumors. It is directed against the platelet-derived growth factor receptor alpha. Olaratumab is used in combination with another cancer medicine called doxorubicin, to treat adults with soft tissue sarcoma. Olaratumab is used when your condition cannot be treated with surgery or radiation. Olaratumab was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis.
LARTRUVO (olaratumab) injection, for intravenous use Initial U.S. Approval: 2016
Generic Name: Olaratumab
Injection: 500 mg/50 mL (10 mg/mL) solution in a single-dose vial
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For LARTRUVO (olaratumab) injection Indications And Usage, Dosage And Administration, Dosage Forms And Strengths and Drug Interactions For More Details
FDA grants accelerated approval to new treatment for advanced soft tissue sarcoma For More Details